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Prader-Willi Syndrome: Symptoms, Causes, and Treatment

What Are the Complications of Prader-Willi Syndrome?

The most common complications that may develop from Prader-Willi syndrome is obesity, and it can be prevented with weight control and treatments.

The complications of PWS often include having abnormal reactions to drugs, especially anesthesia and sedatives. Studies show that people with Prader-Willis syndrome may develop a high pain threshold, meaning an illness or injury does not get medical attention until it reaches its later stages. People with PWS do not experience PWS regularly, except the condition is severe.

Complications related to obesity may include:

  • Type 2 diabetes [3]
  • Sleep apnea
  • Hypertension [4]
  • High cholesterol
  • Heart disease [5]
  • Lung issues

Hormonal complications may include osteoporosis (loss of bone density) and infertility (inability to conceive). Another complication of PWS is binge eating. People with PWS may eat lots of dangerous foods, such as garbage. The compulsion to eat may get very strong that you start to hide food, steal food, or engage in other behaviors because of food.