Family history/ Genetics
You are at significant risk of getting infected if you have someone in your family that suffers from sarcoidosis. It is not a contagious disease, but studies have shown genetic influence in the likelihood of developing the disease. Although it is not inherited, people can have a genetic predisposition to develop the disease, which increases their risk of infection to bacteria, viruses, dust, or chemicals. You may have a genetic disorder that causes your immune system to overreact and start to accumulate cells in a pattern of inflammation called granulomas.
Persons with first-degree relatives, that is, a parent, or a full sibling suffering from the disease are at a higher risk.
Recent studies have shown that the risk of having a first-degree family member with sarcoidosis was 3.73, and it increased to 4.69 if two first-degree family members suffer the condition.
References:
[1] https://emedicine.medscape.com/article/301914-overview
[2] https://www.healthline.com/health/sarcoidosis
[3] https://www.stopsarcoidosis.org/exercise/#:~:text=Sarcoidosis%20patients%20have%20found%20that,battle%20chronic%20pain%20and%20fatigue.
[4] https://www.mayoclinic.org/diseases-conditions/sarcoidosis/symptoms-causes/syc-20350358
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333358/
[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314818/#:~:text=Sarcoidosis%20is%20a%20granulomatous%20disease%20with%20an%20unknown%20etiology.&text=Ethnicity%20plays%20an%20important%20role,disease%20presentation%2C%20and%20clinical%20outcomes.&text=The%20reported%20disease%20incidence%20is,in%20100%2C000%20