Gastrointestinal and Esophagus Involvement
The entire digestive system [7] may be affected, the most characteristic symptoms being the presence of gastroesophageal reflux (passage of acid content from the stomach into the esophagus and mouth, producing pain and burning in the stomach that rise upwards and can lead to difficulty or pain for the passage of food), heavy digestion, stomach pain, digestive bleeding, alterations in the absorption of food, (malabsorption), chronic diarrhea, constipation, rectal prolapse, etc.
The involvement of the esophagus in the process leads to a violation of its function. The gastric reflux damages the lining of the esophagus, which ultimately leads to scarring and narrowing of the esophagus (stricture). In this case, the patient is worried about heartburn, chest pain, and he/she has difficulty swallowing food. [8] Rearrangement of epithelial cells of the esophagus increases the risk of malignant neoplasm – esophageal adenocarcinoma. Intestinal damage is manifested by a violation of the digestive process and manifests itself in the form of diarrhea, abdominal pain, weight loss, anemia, and general weakness.