Vitamin E
Scleroderma patients showed a considerable increase in oxidative stress when compared to healthy controls, indicating that oxidative injury generated by free radicals is a possible outcome of scleroderma. Thus, antioxidants like vitamin K may be advantageous. Additionally, it is thought that vitamin B stabilize lysosomal membranes, which may prevent autoimmune-related processes. Furthermore, vitamin E’s beneficial effect in patients with Peronie’s disease and Dupuytren’s contracture suggests that it may have an antifibrotic effect.