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TDAP Vaccine: Everything You Need to Know

What Potential Negative Effects Could the TDAP Vaccination Have?

The TDAP vaccine is no different from other vaccines in that it carries a small risk of side effects. Thankfully, recorded TDAP side effects are typically minor and go away on their own.

Among the mild to moderate negative effects are:

  • Fatigue
  • Feeling a little pain, redness, or edema at the injection site
  • Headache and body aches
  • Nausea [1]
  • Diarrhea [2]
  • Vomiting
  • Swelling of the entire arm where the vaccine was administered
  • Fever

Rarely reported severe side effects from the DTAP vaccine include the following:

  • A very high fever
  • Symptoms of an allergic reaction, such as hives and facial swelling, within minutes to hours of receiving the vaccine
  • Severe swelling, pain, or bleeding at the injection site.