Non-Hormonal Medications
An example of a non-hormonal drug is tranexamic acid (Lysteda), which is known to help reduce bleeding if it is administered on days when your period is heavy. Although non-hormonal drugs do not reduce fibroid size, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen can help reduce fibroid pain. [4] In most cases, medical therapy tends to be more of a temporizing measure.
MRI-Guided Focused Ultrasound
MRI-guided focused ultrasound is a non-surgical procedure that involves using a magnetic resonance imaging (MRI) system to detect your uterine fibroids and then kill them with high-frequency ultrasound. It is a permanent procedure for eliminating or reducing the size of the fibroid.
MRI-guided focused ultrasound is a safe method for treating uterine fibroids, even if you still want to get pregnant. More research needs to be done to understand the adverse effects of the procedure.