Fatigue and Extremities Edema
If the lungs are not well perfused to function properly [5], it has a ripple effect on the body as there is not enough oxygen to go round. Oxygen is essential for oxidation and energy production. A reduction in its circulating quantity will make you easily fatigued – walking becomes stressful, and thought processes become slower and more difficult. In general, you will feel tired sooner and easier. The effect of the reduction in circulating oxygen level in the brain is dizziness and faintness.
PAH can lead to swelling [6] affecting different parts of the body – legs, free, and ankle. This results from the inability of the kidney to perform its homeostatic activity of removing excess fluid from the body. It is more often a feature of advanced disease.