What is the main cause of Hirschsprung disease?
Scientists believe that multiple genetic mutations linked to abnormal nerve development in the intestines may cause Hirschsprung disease. According to research, about 50% of people with the condition usually have one genetic abnormality.
Conclusion
In most cases, Hirschsprung disease is caught very early in life. Early detection increases the chances of successful treatment. The inability to pass the first stool within 48 hours of birth is the most significant symptom of the condition. The condition may worsen and lead to death if it is not treated on time. Contact your doctor immediately if you notice any signs of Hirschprung disease.
References
[1] https://www.medicalnewstoday.com/articles/318567
[2] https://www.nhs.uk/conditions/malnutrition/
[3] https://www.hopkinsmedicine.org/health/conditions-and-diseases/constipation
[4] https://www.mayoclinic.org/diseases-conditions/intestinal-obstruction/symptoms-causes/syc-20351460
[5] https://www.healthdirect.gov.au/vomiting
[6] https://kidshealth.org/en/parents/fever.html
[7] https://my.clevelandclinic.org/health/diseases/4108-diarrhea