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What Causes Cirrhosis of the Liver

Obstruction of Hepatic Blood Flow

Some diseases can reduce and even obstruct blood flow to the liver, as in Budd-Chiari syndrome. This syndrome is a rare disease in which the formation of large blood clots occurs that leads to the obstruction of the veins that drain the liver, with poor delivery to the organ, often caused by hepatic vein blockage that carries blood away from the liver.

Patients with this syndrome often have abdominal swelling or stretching, vomiting blood, right upper abdomen pain and jaundice. When hepatic vein obstruction get worse, it can lead to cirrhosis and liver failure, threatening patients’ life. Anticoagulants, thrombolytic treatment and some other medicine can help relive these symptoms. Surgery treatments such as liver transplant, venous shunt surgery, and angioplasty and stent placement are recommended if necessary.

Reference:

[1] https://www.mayoclinic.org/diseases-conditions/cirrhosis/symptoms-causes/syc-20351487

[2] https://www.medicalnewstoday.com/articles/172295#causes

[3] https://www.medicalnewstoday.com/articles/172295#causes

[4] https://gi.org/topics/fatty-liver-disease-nafld/#:~:text=Non%2Dalcoholic%20fatty%20liver%20disease%20(NAFLD)%20is%20a%20very,serious%20condition%20called%20fatty%20liver.

[5] https://www.medicalnewstoday.com/articles/172295#causes

[6] https://www.healthline.com/health/cholestasis