Causes of Non-Hodgkin’s Lymphoma
Non-Hodgkin’s lymphoma is a very wide category of cancer; this makes identifying the causes of this condition very complicated. However, researchers have been able to come up with a few cases, these causes are;
Gene Mutation
Non-Hodgkin’s lymphoma is related to bodily changes in some genes; CASP10, BRAF, CARD11, BCL6, and many other genes are mutated in this lymphoma. Specific changes in genes contribute greatly to causing non-Hodgkin’s lymphoma. Tumor suppressor genes [3] and oncogenes [4] are examples of genes in the body that, when altered they lead to cancer. Gene mutation associated with this kind of lymphoma mostly happens as you grow instead of being inherited. Sometimes, changes in the gene are inherited from a parent; therefore, having parents or grandparents who have once had non-Hodgkin’s lymphoma increases the risk of getting it. An acquired gene mutation is derived from contact with radiation, chemicals that lead to cancer and infections. However, most times, this mutation happens for no particular reason. These gene mutations can occur in people without any risk factors.