Depression
People living with bipolar disorder have depressive episodes which are often difficult to differentiate from regular depression. During these low points, they may experience long periods of intense sadness, difficulty sleeping, excessive sleeping, loss of energy, loss of appetite, and suicidal thoughts. They may experience apathy towards activities they used to enjoy or isolate themselves from lovers, their friends, and family.
Antidepressants are often effective for people who suffer from depression. In bipolar patients, treatment with antidepressants alone can have counterproductive effects. In some cases, the drugs may lead to more rapid cycling between depressive and manic states or even a psychotic break.