Overview of Demyelinating Disorders

Nervous System Mia Garnsey

Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is a rare autoimmune condition in which the immune system attacks the nerves of the peripheral nervous system, which includes the nerves outside of the brain and spinal cord. In some forms of GBS, the immune system attacks myelin.

The main symptom of GBS is weakness or numbness and tingling in the legs that often spreads to the arms and torso. It can become as severe as resulting in paralysis. It affects both sides of the body.

Certain infections are known to trigger GBS. One of the most common triggers is an infection with the bacteria Campylobacter jejuni, which causes food poisoning. Experts believe that up to 40% of GBS cases in the United States are due to infections with these bacteria.

Certain viral infections such as Epstein-Barr virus, cytomegalovirus, and the flu can also lead to GBS.

Mia Garnsey April 25, 2022

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