Cancers
In some cases, swollen lymph nodes can be caused by a malignancy, or cancer, such as:
- lymphoma [5]
- Hodgkin disease
- leukemia
- metastases, or the spread of an existing cancer
- Kaposi sarcoma
Certain risk factors make a person more susceptible to developing a malignant lymph problem, such as lymphoma. These include:
- being aged 40 years or older
- being male
- having white skin
People with a malignant lymph node may notice that the node feels hard or rubbery. They may also have systemic symptoms, such as fever, night sweats, and unexplained weight loss.
Swelling in the groin lymph nodes
Sexually transmitted infections (STIs), such as syphilis and gonorrhea, can cause swollen lymph nodes, especially in the groin area. Lymph nodes in the groin are also known as inguinal lymph nodes.
Recurring infections, lower body infections, and injury to the legs can also cause swollen lymph nodes in the groin.