Migraine Headache Prophylaxis: 8 Preventive Therapies

Migraine Mia Garnsey

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Non-steroidal anti-inflammatory drugs (NSAIDs) are administered to help reduce inflammation and pain. This is done by blocking the production of prostaglandins. Although NSAIDs are most commonly used for the prevention of menstrual migraine, or migraine attacks that occur during menstruation.

Its Effectiveness

The evidence-based guidelines from the American Academy of Neurology and the American Headache Society confirm that NSAIDs show modest benefits for the prevention of migraine headaches. Examples of NSAIDs that demonstrated benefits in clinical trials include flurbiprofen, naproxen sodium, ketoprofen, and mefenamic acid. However, it is not advisable to use NSAIDs for long-term continuous treatment to treat migraine prophylaxis, this is because it can lead to medication overuse headaches.

Its Side Effects

Certain side effects associated with using NSAIDs to treat migraine prophylaxis include headaches, dizziness, drowsiness, gastrointestinal symptoms, and in some cases organ damage. NSAIDs as a preventive measure for migraine headaches during menstruation should be taken 2 to 3 days before menstruation and during the first 3 days of it.

Mia Garnsey March 3, 2022

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