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Tiredness (Fatigue): Causes, Tests, and Treatment

Medical condition that causes fatigue

Fatigue is a symptom of a wide range of diseases, disorders and deficiencies affecting various parts of your body. There are hundreds of conditions and disorders that can cause fatigue. Some of the most common causes of fatigue include:

Infections

Fatigue can be traced to many infections including:

  • HIV
  • Mononucleosis
  • COVID-19
  • Pneumonia
  • Influenza
  • Heart and lung problems
  • Lyme disease

Fatigue is a common symptom of cardiovascular and lung conditions, such as:

  • Heart disease
  • Postural orthostatic tachycardia syndrome (POTS) [2]
  • Emphysema
  • Chronic obstructive pulmonary disease (COPD) [3]
  • Congestive heart failure