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Austedo: Uses, Dosage, Side Effects and More

Warnings

Doctors advise people with liver disease, untreated or unregulated depression and suicidal thoughts to stay away from austedo. Do not use this drug if you have taken reserpine (Serpalan, Renese-R) in the past 20 days, or if you have used an MAO inhibitor (isocarboxazid, linezolid, rasagiline, selegiline, and others) in the past 14 days.

Take note of changes in your mood, feelings, thoughts, or behaviors. Tell your doctor about any new or exacerbating symptoms to your doctor. Your doctor will need to observe your progress while you are using Austedo.

You must not take Austedo if you are allergic to deutetrabenazine, or if you have:

  • untreated or uncontrolled depression
  • thoughts about suicide or hurting yourself
  • liver disease
  • If you have recently taken tetrabenazine (Xenazine) or valbenazine (Ingrezza).

Do not use Austedo if you have taken reserpine (Serpalan, Renese-R) in the past 20 days, or if you have used an MAO inhibitor in the past 14 days. A harmful drug interaction could occur.  Examples MAO inhibitors are isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure Austedo is safe for you, talk to your doctor if you have ever experienced:

  • depression, anxiety, nervousness, or agitation
  • mental illness or psychosis
  • suicidal thoughts or actions
  • breast cancer [1]
  • a heart rhythm disorder
  • long QT syndrome (in you or a family member)
  • an electrolyte imbalance (such as low levels of potassium or magnesium [2] in your blood).

People with Huntington’s disease are more susceptible to depression and having suicidal thoughts or behaviours. Consuming Austedo may further increase this risk. However, the benefits of using this drug (improvement in daily living) may outweigh any suicidal risks.

Consuming deutetrabenazine may cause symptoms similar to Parkinson’s disease such as resting tremor, stiff muscles, slow movements, difficulty maintaining balance and walking. Ask your doctor about your risk. Your doctor should observe your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

The effects of deutetrabenazine on an unborn baby is still unknown. You must tell your doctor if you are pregnant or you plan on becoming pregnant. It may not be safe to breastfeed while taking deutetrabenazine. Speak to your doctor about any risk. Austedo should not be used by people younger than 18 years old.