MAO inhibitors & COMT inhibitors (Tasmar, Comtan)
Selegiline is a group of medications that includes Eldepryl and deprenyl. The medication helps preserve the available dopamine by slowing down or stopping its destruction. Some experts believe that this medication can help improve Parkinson’s disease in the early stage of the condition. Most patients tolerate the drug properly. Its side effects include vomiting and nausea [6]. Eldepryl/deprenyl can react with other drugs like Demerol and some depression medications. It is important to speak with your healthcare provider about other drugs you are using before using deprenyl or Eldepryl
Doctors prescribe COMT inhibitors to boost the efficiency of Levodopa. Dopamine can be preserved and utilized properly if COMT is inhibited.