Sex, Joints Inflammation & Nerve Damage
This disease usually develops more in females [9] than in males. This could be because the region of the carpal tunnel is comparatively smaller than that of men, and there is a higher potential of developing the syndrome with a slight error. There may also be smaller carpal tunnels in women who have carpal tunnel syndrome than in women who do not have the condition.
The tendons in your wrist may be affected by diseases that are characterized by inflammatory symptoms in joints, such as rheumatoid arthritis, causing pressure on the median nerve.
The risk of nerve damage, especially median nerve damage, is increased by certain chronic illnesses, such as diabetes.