Symptoms
The clinical manifestations are characterized by erythematous, exudative, and lichenoid eruptions, which are accompanied by intense itching. Atopic dermatitis is often associated with abnormalities in skin barrier function, sensitization to allergens, and recurrent skin infections. Dysbiosis of the skin microbiota may also play a key role in the development of atopic dermatitis. It has been scientifically proven that atopic dermatitis is a skin symptom of a systemic disorder and often appears as the first step in the so-called “atopic march” that causes bronchial asthma, food allergies, and allergic rhinitis. [6]
The general symptoms of atopic dermatitis
Xerosis/Dry Skin
Xerosis, or dry skin, is a very common skin pathology, often it is a “launching pad” for the development of various dermatoses such as atopic dermatitis. [7] With xerosis, the skin peels off with varying degrees of severity, small cracks appear, and the skin surface becomes rough even to the touch. All of these signs appear due to a decrease in moisture in the surface layers of the skin. Due to dehydration with an increase in transepidermal water loss, the barrier function is impaired.
Xerosis can be both a manifestation of dermatological diseases (ichthyosis, atopic dermatitis, etc.), and an independent phenomenon that appears at certain time periods under the influence of various factors.