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FOLFOX Chemotherapy – Side Effects, Regimen and More

FOLFOX Regimen

FOLFOX is generally administered intravenously directly into your bloodstream. You may receive it via a short tube known as a cannula that links with a vein in your arm. You may also receive it via a peripherally inserted central catheter (PICC), which is a long tube that can be placed into your arm to release medications into the large central veins near your heart.

FOLFOX is usually administered in 2-week cycles. Some people may get more or fewer cycles, but it must not be more than 12. The type of treatment you get depends on the type of FOLFOX your doctor recommends. Here is an explanation of what FOLFOX treatment may look like:

On the first day, your doctor will administer:

  • Oxaliplatin administered into your bloodstream 2 hours after a drip
  • Folinic acid released into your bloodstream at the same time as the oxaliplatin
  • Fluorouracil injected through your cannula or PICC
  • Fluorouracil infusion over 22 hours through a drip or pump

On the second day, your doctor will administer:

  • Folinic acid is injected or administered through a drip for 2 hours
  • Fluorouracil administered into your bloodstream
  • Fluorouracil infusion over 22 hours through a drip or pump

You will not receive any therapy from days 3 to 14 until your next cycle begins.