A liver condition
Bilirubin accumulation in the blood can be brought on by any disorder that impairs the liver’s ability to operate. This happens when the liver’s capacity to filter and process bilirubin from the blood decreases.
Your liver’s performance may be impacted by a number of factors, including:
- cirrhosis [2]
- liver cancer [3]
- liver-related autoimmune diseases such autoimmune hepatitis or primary biliary cholangitis
The following are typical signs of liver dysfunction:
- abdominal pain or swelling if you have jaundice
- Edema
- swelling of the ankles or legs
- fatigue
- nausea or vomiting
- easy bruising
- pale, red, or black stools and dark urine
- rough skin