Heart rhythm drugs
Using certain heart rhythm medications with carvedilol can cause more dangerous side effects. The combination may reduce your heart rate or blood pressure, or worsen a heart blockage. In some cases, your doctor will have to watch you closely for side effects or change the dosage of carvedilol or your heart rhythm drug.
Examples of these drugs include:
- amiodarone
- bretylium
- quinidine
- digoxin
- disopyramide
- encainide
- flecainide
- propafenone
- procainamide
- sotalol
Blood pressure drug
Taking clonidine with carvedilol can reduce your blood pressure and heart rate even further. If you’re switching to carvedilol from clonidine, your doctor will gradually take you off clonidine. You’ll start carvedilol several days after stopping clonidine. If you need both drugs, your doctor will observe you for low blood pressure and low heart rate. If you’re on both drugs and both need to be stopped, your doctor will stop your treatment with carvedilol first and clonidine a few days later.