Migraine Headache Prophylaxis: 8 Preventive Therapies

Migraine headache is a severe form of pain in the head. The Migraine Research Foundation has discovered that it affects about 39 million adults and children in the United States. Chronic migraine headaches can be debilitating and will most likely to affect your quality of life. It can be very unbearable that your doctor will prefer to have you admitted in the hospital.

However, there are effective ways to treat migraine headaches. First-line preventive therapies, or prophylaxis, can help reduce the frequency and severity of these headaches. In this article, we will discuss eight of the most common preventive therapies for migraine prophylaxis. We will also discuss the effectiveness of each of them and whatever side effect might be attached to them.


Antidepressants are a group of medication that works by altering the neurotransmitter in the brain. They are used to treat mental health conditions such as depression and anxiety. Antidepressants medications include serotonin, selective serotonin reuptake inhibitors (SSIRs), [1] and norepinephrine reuptake inhibitors (SNRIs).