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Low Chloride Levels (Hypochloremia): Causes, Risks, And More

Metabolic Alkalosis

Metabolic alkalosis, also known as blood pH, occurs due to:

  • Loss of hydrogen ions
  • Increased bicarbonate production/intake
  • Decreased bicarbonate excretion

Other causes of metabolic alkalosis include:

  • Dehydration [1]
  • Vomiting
  • Medications, such as diuretics [2] that increase the amount of hydrogen ion you urinate.
  • Kidney disorders that reduce the urination of HCO3-
  • Consuming excess antacids

The reduction of a positively charged electrolyte, such as hydrogen and the accumulation of a negatively charged electrolyte, such as bicarbonate increases the elimination of chloride to create a balance between positive and negative charges. Consuming high amounts of sodium bicarbonate results in blood alkalosis. It may also result in chloride being exchanged for bicarbonate to maintain blood neutrality.