Drug Interactions
Like other NSAIDs, Nabumetone oral tablets can interact with other drugs, vitamins, or herbs you consume. An interaction occurs when another substance alters the functions of a drug. This can be highly dangerous and, in some cases, lead to death. This is why it is essential to talk to your doctor about any other substance you may be taking before using Nabumetone so that they can guide you.
Let’s discuss some medications that you should not take with nabumetone.
- Ketorolac: This is an anti-inflammatory drug. It would help if you did not take it with Nabumetone because it makes you more susceptible to bleeding and ulcers.
- Omacetaxine: This is chemotherapy medication. It would help if you did not take this with nabumetone because it increases your risk for bleeding and ulcers [2].
When you use certain drugs with Nabumetone, it increases the side effects of both drugs. These drugs are Warfarin, aspirin and other NSAIDs like ibuprofen, naproxen and celecoxib. You may Increase the side effects of some medications you use with Nabumetone. Some of these drugs are:
- Methotrexate: Worsened side effects of methotrexate are insufficient white blood cells, red blood cells, and platelets in the body and a decrease in the body’s ability to fight infections.
- Lithium: Worsened side effects of lithium are nausea, vomiting, diarrhea [3], drowsiness, muscle weakness, tremor, loss of coordination, blurred vision, and ringing in your ears.
Some medications should be avoided when using Nabumetone because they reduce its potency. Examples are:
- Angiotensin-converting enzyme (ACE) inhibitors: Drugs like captopril, enalapril, and lisinopril should not be taken with Nabumetone. Your doctor will observe your blood pressure properly if you use these drugs.
- Diuretics (water pills) such as thiazide diuretics (including chlorothiazide and hydrochlorothiazide) and furosemide. Your doctor will observe your fluid levels, blood pressure and kidney activities if you have to take these medications.